Molecular basis for DNA strand displacement by NHEJ repair polymerases

The non-homologous end-joining (NHEJ) pathway repairs DNA double-strand breaks (DSBs) in all domains of life. Archaea and bacteria utilize a conserved set of multifunctional proteins in a pathway termed Archaeo-Prokaryotic (AP) NHEJ that facilitates DSB repair. Archaeal NHEJ polymerases (Pol) are ca...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Bartlett, Edward J., Brissett, Nigel C., Plocinski, Przemyslaw, Carlberg, Tom, Doherty, Aidan J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797286/
https://ncbi.nlm.nih.gov/pubmed/26405198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv965
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items