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Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates
Nonhomologous end-joining (NHEJ) pathways repair DNA double-strand breaks (DSBs) in eukaryotes and many prokaryotes, although it is not reported to operate in the third domain of life, archaea. Here, we describe a complete NHEJ complex, consisting of DNA ligase (Lig), polymerase (Pol), phosphoestera...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670387/ https://ncbi.nlm.nih.gov/pubmed/23671117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302616110 |
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