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Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates

Nonhomologous end-joining (NHEJ) pathways repair DNA double-strand breaks (DSBs) in eukaryotes and many prokaryotes, although it is not reported to operate in the third domain of life, archaea. Here, we describe a complete NHEJ complex, consisting of DNA ligase (Lig), polymerase (Pol), phosphoestera...

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Bibliografski detalji
Glavni autori: Bartlett, Edward J., Brissett, Nigel C., Doherty, Aidan J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670387/
https://ncbi.nlm.nih.gov/pubmed/23671117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302616110
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