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Impaired Resection of Meiotic Double-Strand Breaks Channels Repair to Nonhomologous End Joining in Caenorhabditis elegans

Repair of double-strand DNA breaks (DSBs) by the homologous recombination (HR) pathway results in crossovers (COs) required for a successful first meiotic division. Mre11 is one member of the MRX/N (Mre11, Rad50, and Xrs2/Nbs1) complex required for meiotic DSB formation and for resection in Saccharo...

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Detalhes bibliográficos
Main Authors: Yin, Yizhi, Smolikove, Sarit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700128/
https://ncbi.nlm.nih.gov/pubmed/23671188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00055-13
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