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Gene Conversion and End-Joining-Repair Double-Strand Breaks in the Caenorhabditis elegans Germline

Excision of a Mos1 transposon in the germline of Caenorhabditis elegans generates a double-strand break in the chromosome. We demonstrate that breaks are most prominently repaired by gene conversion from the homolog, but also rarely by nonhomologous end-joining. In some cases, gene conversion events...

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Detalhes bibliográficos
Main Authors: Robert, Valérie J., Davis, M. Wayne, Jorgensen, Erik M., Bessereau, Jean-Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535717/
https://ncbi.nlm.nih.gov/pubmed/18757928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.089698
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