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Biochemical and Phenotypic Abnormalities in Kynurenine Aminotransferase II-Deficient Mice
Kynurenic acid (KYNA) can act as an endogenous modulator of excitatory neurotransmission and has been implicated in the pathogenesis of several neurological and psychiatric diseases. To evaluate its role in the brain, we disrupted the murine gene for kynurenine aminotransferase II (KAT II), the prin...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC479723/ https://ncbi.nlm.nih.gov/pubmed/15282294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.16.6919-6930.2004 |
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