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TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction
TRIM5α is an interferon-inducible retroviral restriction factor that prevents infection by inducing the abortive disassembly of capsid cores recognized by its C-terminal PRY/SPRY domain. The mechanism by which TRIM5α mediates the disassembly of viral cores is poorly understood. Previous studies demo...
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| 發表在: | J Virol |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794682/ https://ncbi.nlm.nih.gov/pubmed/26764007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03033-15 |
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