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Identification of residues within the L2 region of rhesus TRIM5α that are required for retroviral restriction and cytoplasmic body localization

The intracellular restriction factor TRIM5α, inhibits infection by numerous retroviruses in a species-specific manner. The best characterized example of this restriction is the TRIM5α protein from rhesus macaques (rhTRIM5α), which potently inhibits HIV-1 infection. TRIM5α localizes to cytoplasmic as...

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Detalhes bibliográficos
Main Authors: Sastri, Jaya, O’Connor, Christopher, Danielson, Cindy M., McRaven, Michael, Perez, Patricio, Griffero, Felipe Diaz, Campbell, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914212/
https://ncbi.nlm.nih.gov/pubmed/20633914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.06.015
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