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Recent Insights into the Mechanism and Consequences of TRIM5α Retroviral Restriction

The cellular factor TRIM5α inhibits infection by numerous retroviruses in a species-specific manner. The TRIM5α protein from rhesus macaques (rhTRIM5α) restricts infection by HIV-1 while human TRIM5α (huTRIM5α) restricts infection by murine leukemia virus (MLV). In owl monkeys a related protein TRIM...

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Detalhes bibliográficos
Main Authors: Sastri, Jaya, Campbell, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048830/
https://ncbi.nlm.nih.gov/pubmed/21247355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2010.0367
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