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TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction

TRIM5α is an interferon-inducible retroviral restriction factor that prevents infection by inducing the abortive disassembly of capsid cores recognized by its C-terminal PRY/SPRY domain. The mechanism by which TRIM5α mediates the disassembly of viral cores is poorly understood. Previous studies demo...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Imam, Sabrina, Talley, Sarah, Nelson, Rachel S., Dharan, Adarsh, O'Connor, Christopher, Hope, Thomas J., Campbell, Edward M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794682/
https://ncbi.nlm.nih.gov/pubmed/26764007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03033-15
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