K63-Linked Ubiquitin Is Required for Restriction of HIV-1 Reverse Transcription and Capsid Destabilization by Rhesus TRIM5α

TRIM5α is an antiviral restriction factor that inhibits retroviral infection in a species-specific fashion. TRIM5α binds to and forms assemblies around the retroviral capsid. Following binding, poorly understood, ubiquitin-dependent events lead to the disassembly of the viral core, prior to the accu...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Imam, Sabrina, Kömürlü, Sevnur, Mattick, Jessica, Selyutina, Anastasia, Talley, Sarah, Eddins, Amani, Diaz-Griffero, Felipe, Campbell, Edward M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600202/
https://ncbi.nlm.nih.gov/pubmed/31068426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00558-19
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky