TRIM5α-Mediated Ubiquitin Chain Conjugation Is Required for Inhibition of HIV-1 Reverse Transcription and Capsid Destabilization

Rhesus macaque TRIM5α (rhTRIM5α) is a retroviral restriction factor that inhibits HIV-1 infection. Previous studies have revealed that TRIM5α restriction occurs via a two-step process. The first step is restriction factor binding, which is sufficient to inhibit infection. The second step, which is s...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Campbell, Edward M., Weingart, Jared, Sette, Paola, Opp, Silvana, Sastri, Jaya, O'Connor, Sarah K., Talley, Sarah, Diaz-Griffero, Felipe, Hirsch, Vanessa, Bouamr, Fadila
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Virus-Cell Interactions
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733990/
https://ncbi.nlm.nih.gov/pubmed/26676782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01948-15
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