Ubiquitin conjugation to Gag is essential for ESCRT-mediated HIV-1 budding

BACKGROUND: HIV-1 relies on the host ESCRTs for release from cells. HIV-1 Gag engages ESCRTs by directly binding TSG101 or Alix. ESCRTs also sort ubiquitinated membrane proteins through endosomes to facilitate their lysosomal degradation. The ability of ESCRTs to recognize and process ubiquitinated...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sette, Paola, Nagashima, Kunio, Piper, Robert C, Bouamr, Fadila
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751857/
https://ncbi.nlm.nih.gov/pubmed/23895345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-79
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires