Ubiquitin conjugation to Gag is essential for ESCRT-mediated HIV-1 budding

BACKGROUND: HIV-1 relies on the host ESCRTs for release from cells. HIV-1 Gag engages ESCRTs by directly binding TSG101 or Alix. ESCRTs also sort ubiquitinated membrane proteins through endosomes to facilitate their lysosomal degradation. The ability of ESCRTs to recognize and process ubiquitinated...

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Bibliografiset tiedot
Päätekijät: Sette, Paola, Nagashima, Kunio, Piper, Robert C, Bouamr, Fadila
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2013
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751857/
https://ncbi.nlm.nih.gov/pubmed/23895345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-79
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