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Basic Residues in the Nucleocapsid Domain of Gag Are Critical for Late Events of HIV-1 Budding
The p6 region of HIV-1 Gag contains two late (L) domains, PTAP and LYPXnL, that bind the cellular proteins Tsg101 and Alix, respectively. These interactions are thought to recruit members of the host fission machinery (ESCRT) to facilitate HIV-1 release. Here we report a new role for the p6-adjacent...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067763/ https://ncbi.nlm.nih.gov/pubmed/21159863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01562-10 |
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