The Nucleocapsid Region of HIV-1 Gag Cooperates with the PTAP and LYPX(n)L Late Domains to Recruit the Cellular Machinery Necessary for Viral Budding

HIV-1 release is mediated through two motifs in the p6 region of Gag, PTAP and LYPX(n)L, which recruit cellular proteins Tsg101 and Alix, respectively. The Nucleocapsid region of Gag (NC), which binds the Bro1 domain of Alix, also plays an important role in HIV-1 release, but the underlying mechanis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dussupt, Vincent, Javid, Melodi P., Abou-Jaoudé, Georges, Jadwin, Joshua A., de La Cruz, Jason, Nagashima, Kunio, Bouamr, Fadila
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651531/
https://ncbi.nlm.nih.gov/pubmed/19282983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000339
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados