The Nucleocapsid Region of HIV-1 Gag Cooperates with the PTAP and LYPX(n)L Late Domains to Recruit the Cellular Machinery Necessary for Viral Budding

HIV-1 release is mediated through two motifs in the p6 region of Gag, PTAP and LYPX(n)L, which recruit cellular proteins Tsg101 and Alix, respectively. The Nucleocapsid region of Gag (NC), which binds the Bro1 domain of Alix, also plays an important role in HIV-1 release, but the underlying mechanis...

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Bibliografische gegevens
Hoofdauteurs: Dussupt, Vincent, Javid, Melodi P., Abou-Jaoudé, Georges, Jadwin, Joshua A., de La Cruz, Jason, Nagashima, Kunio, Bouamr, Fadila
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2009
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651531/
https://ncbi.nlm.nih.gov/pubmed/19282983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000339
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