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Targeting Calcium Signaling To Induce Epigenetic Reactivation of Tumor Suppressor Genes in Cancer
Targeting epigenetic pathways is a promising approach for cancer therapy. Here, we report on the unexpected finding that targeting calcium signaling can reverse epigenetic silencing of tumor suppressor genes (TSGs). In a screen for drugs that reactivate silenced gene expression in colon cancer cells...
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Publicado no: | Cancer Res |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794357/ https://ncbi.nlm.nih.gov/pubmed/26719529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2391 |
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