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INTESTINE-DERIVED MATRIX METALLOPROTEINASE-8 IS A CRITICAL MEDIATOR OF POLYMICROBIAL PERITONITIS
OBJECTIVE: Inhibition of matrix metalloproteinase-8 (MMP8) improves survival following cecal ligation and puncture (CLP) in mice, making it a potential therapeutic target. In the current study we expand our understanding of the role of MMP8 in sepsis by employing an adoptive transfer approach and al...
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| Publicado no: | Crit Care Med |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792672/ https://ncbi.nlm.nih.gov/pubmed/26496446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000001374 |
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