MKP1 mediates chemosensitizer effects of E1a in response to cisplatin in non-small cell lung carcinoma cells

The adenoviral gene E1a is known to enhance the antitumor effect of cisplatin, one of the cornerstones of the current cancer chemotherapy. Here we study the molecular basis of E1a mediated sensitivity to cisplatin in an experimental model of Non-small cell lung cancer. Our data show how E1a blocks t...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Cimas, Francisco J., Callejas-Valera, Juan L., Pascual-Serra, Raquel, García-Cano, Jesus, Garcia-Gil, Elena, De la Cruz-Morcillo, Miguel, Ortega-Muelas, Marta, Serrano-Oviedo, Leticia, Gutkind, J. Silvio, Sánchez-Prieto, Ricardo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2015
Konular:
Priority Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792544/
https://ncbi.nlm.nih.gov/pubmed/26689986
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