Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance

Resistance to cisplatin is a major challenge in the current cancer therapy. In order to explore new therapeutic strategies to cisplatin resistance, we evaluated, in a model of lung cancer (H1299 and H460 cell lines), the nature of the pathways leading to cell death. We observed that H1299 displayed...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: García-Cano, Jesús, Ambroise, Gorbatchev, Pascual-Serra, Raquel, Carrión, Maria Carmen, Serrano-Oviedo, Leticia, Ortega-Muelas, Marta, Cimas, Francisco J., Sabater, Sebastià, Ruiz-Hidalgo, María José, Perez, Isabel Sanchez, Mas, Antonio, Jalón, Félix A., Vazquez, Aimé, Sánchez-Prieto, Ricardo
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558170/
https://ncbi.nlm.nih.gov/pubmed/26036632
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