E1a promotes c-Myc-dependent replicative stress: Implications in glioblastoma radiosensitization

The E1a gene from adenovirus is known to be a potent inducer of chemo/radiosensitivity in a wide range of tumors. However, the molecular bases of its radiosensitizer properties are still poorly understood. In an attempt to study this effect, U87MG cells, derived from a radio-resistant tumor as gliob...

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Bibliographische Detailangaben
Hauptverfasser: Valero, María Llanos, Cimas, Francisco Jose, Arias, Laura, Melgar-Rojas, Pedro, García, Elena, Callejas-Valera, Juan Luis, García-Cano, Jesús, Serrano-Oviedo, Leticia, Ángel de la Cruz-Morcillo, Miguel, Sánchez-Pérez, Isabel, Sánchez-Prieto, Ricardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925735/
https://ncbi.nlm.nih.gov/pubmed/24196438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26754
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