Mismatch repair gene defects in sporadic colorectal cancer enhance immune surveillance

BACKGROUND: There is evidence that colorectal cancers (CRC) with DNA mismatch repair deficiency (MMR-D) are associated with a better prognosis than the generality of large bowel malignancies. Since an active immune surveillance process has been demonstrated to influence CRC outcome, we investigated...

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Publicado en:Oncotarget
Autores principales: Scarpa, Marco, Ruffolo, Cesare, Canal, Fabio, Scarpa, Melania, Basato, Silvia, Erroi, Francesca, Fiorot, Alain, Dall'Agnese, Lucia, Pozza, Anna, Porzionato, Andrea, Castagliuolo, Ignazio, Dei Tos, Angelo P., Bassi, Nicolò, Castoro, Carlo
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791244/
https://ncbi.nlm.nih.gov/pubmed/26496037
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