Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions and its expression is increased by oxidative stress through STAT3 in colon cancer cells

BACKGROUND: One of the most potent costimulatory molecules involved in the recognition and killing of tumor cells is CD80. However, its role and the molecular mechanisms regulating its expression in sporadic colorectal carcinogenesis remain elusive. Here, we provide evidence for CD80 overexpression...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Exp Clin Cancer Res
Hoofdauteurs: Marchiori, Chiara, Scarpa, Melania, Kotsafti, Andromachi, Morgan, Susan, Fassan, Matteo, Guzzardo, Vincenza, Porzionato, Andrea, Angriman, Imerio, Ruffolo, Cesare, Sut, Stefania, Dall’Acqua, Stefano, Bardini, Romeo, De Caro, Raffaele, Castoro, Carlo, Scarpa, Marco, Castagliuolo, Ignazio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509793/
https://ncbi.nlm.nih.gov/pubmed/31072360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1205-0
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items