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Mismatch repair gene defects in sporadic colorectal cancer enhance immune surveillance
BACKGROUND: There is evidence that colorectal cancers (CRC) with DNA mismatch repair deficiency (MMR-D) are associated with a better prognosis than the generality of large bowel malignancies. Since an active immune surveillance process has been demonstrated to influence CRC outcome, we investigated...
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Veröffentlicht in: | Oncotarget |
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Hauptverfasser: | , , , , , , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Impact Journals LLC
2015
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4791244/ https://ncbi.nlm.nih.gov/pubmed/26496037 |
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