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MLH1 Deficiency Down-Regulates TLR4 Expression in Sporadic Colorectal Cancer

Patients with mismatch repair (MMR)-deficient colorectal cancer (CRC) have a more favorable prognosis than patients with tumors with intact MMR. In order to obtain further insights on the reasons for this different outcome, we investigated the interplay between MMR genes and TLR4/MyD88 signaling. Th...

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Bibliografske podrobnosti
izdano v:Front Mol Biosci
Main Authors: Scarpa, Melania, Ruffolo, Cesare, Kotsafti, Andromachi, Canal, Fabio, Erroi, Francesca, Basato, Silvia, DallAgnese, Lucia, Fiorot, Alain, Pozza, Anna, Brun, Paola, Bassi, Nicol, Dei Tos, Angelo, Castoro, Carlo, Castagliuolo, Ignazio, Scarpa, Marco
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8139190/
https://ncbi.nlm.nih.gov/pubmed/34026821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.624873
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