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Nanopore Detection of 8-Oxoguanine in the Human Telomere Repeat Sequence
[Image: see text] The human telomere repeat sequence 5′-TTAGGG-3′ is a hot spot for oxidation at guanine, yielding 8-oxo-7,8-dihydroguanine (OG), a biomarker of oxidative stress. Telomere shortening resulting from oxidation will ultimately induce cellular senescence. In this study, α-hemolysin (α-HL...
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| Publicado no: | ACS Nano |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2015
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4790916/ https://ncbi.nlm.nih.gov/pubmed/25768204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b00722 |
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