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Crown ether–electrolyte interactions permit nanopore detection of individual DNA abasic sites in single molecules

DNA abasic (AP) sites are one of the most frequent lesions in the genome and have a high mutagenic potential if unrepaired. After selective attachment of 2-aminomethyl-18-crown-6 (18c6), individual AP lesions are detected during electrophoretic translocation through the bacterial protein ion channel...

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Sonraí Bibleagrafaíochta
Main Authors: An, Na, Fleming, Aaron M., White, Henry S., Burrows, Cynthia J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406832/
https://ncbi.nlm.nih.gov/pubmed/22711805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201669109
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