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Synthesis of Site-specific Crown Ether Adducts to DNA Abasic Sites, 8-Oxo-7,8-dihydro-2’-deoxyguanosine and 2’-Deoxycytidine

Formation of adducts to DNA is of great benefit to DNA sequencing and damage detection technology and to enzymology. Here we describe the synthesis and characterization procedures of 18-crown-6 adducts formed to abasic (AP) sites, 8-oxo-7,8-dihydro-2’-deoxyguanosine (OG), and 2’-deoxycytidine (C) re...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: An, Na, Fleming, Aaron M., Rosecrans, Nicole C., Liao, Yi, Burrows, Cynthia J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482849/
https://ncbi.nlm.nih.gov/pubmed/31016693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9216-4_2
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