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Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes
OBJECTIVES: In response to reports of Trypanosoma brucei resistance to the nitroaromatic drug nifurtimox, we evaluated the potential of antituberculosis nitrofuran isoxazolines as inhibitors of trypanosome growth. METHODS: The susceptibility of T. brucei brucei was assessed in vitro. The lowest effe...
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| Опубликовано в: : | J Antimicrob Chemother |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4790617/ https://ncbi.nlm.nih.gov/pubmed/26682963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv417 |
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