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Myosin regulatory light chain phosphorylation enhances cardiac β-myosin in vitro motility under load
Familial hypertrophic cardiomyopathy (HCM) is characterized by left ventricular hypertrophy and myofibrillar disarray, and often results in sudden cardiac death. Two HCM mutations, N47K and R58Q, are located in the myosin regulatory light chain (RLC). The RLC mechanically stabilizes the myosin lever...
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| Publicado no: | Arch Biochem Biophys |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4790447/ https://ncbi.nlm.nih.gov/pubmed/26116789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2015.06.014 |
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