The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon

OBJECTIVE: ATG16L1 is an autophagy gene known to control host immune responses to viruses and bacteria. Recently, a non-synonymous single-nucleotide polymorphism in ATG16L1 (Thr300Ala), previously identified as a risk factor in Crohn's disease (CD), was associated with more favourable clinical...

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Detaylı Bibliyografya
Yayımlandı:Gut
Asıl Yazarlar: Grimm, Wesley A, Messer, Jeannette S, Murphy, Stephen F, Nero, Thomas, Lodolce, James P, Weber, Christopher R, Logsdon, Mark F, Bartulis, Sarah, Sylvester, Brooke E, Springer, Amanda, Dougherty, Urszula, Niewold, Timothy B, Kupfer, Sonia S, Ellis, Nathan, Huo, Dezheng, Bissonnette, Marc, Boone, David L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group 2016
Konular:
Colon
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789828/
https://ncbi.nlm.nih.gov/pubmed/25645662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308735
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