Expression of TNFAIP3 in intestinal epithelial cells protects from DSS- but not TNBS-induced colitis

Intestinal epithelial cells (IEC) maintain gastrointestinal homeostasis by providing a physical and functional barrier between the intestinal lumen and underlying mucosal immune system. The activation of NF-κB and prevention of apoptosis in IEC are required to maintain the intestinal barrier and pre...

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Detalhes bibliográficos
Main Authors: Rhee, Lesley, Murphy, Stephen F., Kolodziej, Lauren E., Grimm, Wesley A., Weber, Christopher R., Lodolce, James P., Chang, Jonathan E., Bartulis, Sarah J., Messer, Jeannette S., Schneider, Jeff R., Paski, Shirley, Nero, Thomas M., Boone, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Inflammation/Immunity/Mediators
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404569/
https://ncbi.nlm.nih.gov/pubmed/22595989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00077.2012
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