Expression of TNFAIP3 in intestinal epithelial cells protects from DSS- but not TNBS-induced colitis

Intestinal epithelial cells (IEC) maintain gastrointestinal homeostasis by providing a physical and functional barrier between the intestinal lumen and underlying mucosal immune system. The activation of NF-κB and prevention of apoptosis in IEC are required to maintain the intestinal barrier and pre...

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Main Authors: Rhee, Lesley, Murphy, Stephen F., Kolodziej, Lauren E., Grimm, Wesley A., Weber, Christopher R., Lodolce, James P., Chang, Jonathan E., Bartulis, Sarah J., Messer, Jeannette S., Schneider, Jeff R., Paski, Shirley, Nero, Thomas M., Boone, David L.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Inflammation/Immunity/Mediators
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404569/
https://ncbi.nlm.nih.gov/pubmed/22595989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00077.2012
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