African-Derived Genetic Polymorphisms in TNFAIP3 Mediate Risk for Autoimmunity

The TNF α-induced protein 3 (TNFAIP3) is an ubiquitin-modifying enzyme and an essential negative regulator of inflammation. Genome-wide association studies have implicated the TNFAIP3 locus in susceptibility to autoimmune disorders in European cohorts, including rheumatoid arthritis, coronary artery...

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Bibliografiske detaljer
Main Authors: Lodolce, James P., Kolodziej, Lauren E., Rhee, Lesley, Kariuki, Silvia N., Franek, Beverly S., McGreal, Nancy M., Logsdon, Mark F., Bartulis, Sarah J., Perera, Minoli A., Ellis, Nathan A., Adams, Erin J., Hanauer, Stephen B., Jolly, Meenakshi, Niewold, Timothy B., Boone, David L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307531/
https://ncbi.nlm.nih.gov/pubmed/20483768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000324
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