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Promoter Variant of PIK3C3 Is Associated with Autoimmunity against Ro and Sm Epitopes in African-American Lupus Patients

The PIK3C3 locus was implicated in case-case genome-wide association study of systemic lupus erythematosus (SLE) which we had performed to detect genes associated with autoantibodies and serum interferon-alpha (IFN-α). Herein, we examine a PIK3C3 promoter variant (rs3813065/-442 C/T) in an independe...

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Detaylı Bibliyografya
Asıl Yazarlar: Silvia N. Kariuki, Beverly S. Franek, Rachel A. Mikolaitis, Tammy O. Utset, Meenakshi Jolly, Andrew D. Skol, Timothy B. Niewold
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Limited 2010-01-01
Seri Bilgileri:Journal of Biomedicine and Biotechnology
Online Erişim:http://dx.doi.org/10.1155/2010/826434
Etiketler: Etiketle
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