Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus

INTRODUCTION: Systemic lupus erythematosus (SLE) is a highly heterogeneous disorder, characterized by differences in autoantibody profile, serum cytokines, and clinical manifestations. SLE-associated autoantibodies and high serum interferon alpha (IFN-α) are important heritable phenotypes in SLE whi...

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Autori principali: Kariuki, Silvia N, Franek, Beverly S, Kumar, Akaash A, Arrington, Jasmine, Mikolaitis, Rachel A, Utset, Tammy O, Jolly, Meenakshi, Crow, Mary K, Skol, Andrew D, Niewold, Timothy B
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945049/
https://ncbi.nlm.nih.gov/pubmed/20659327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3101
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