Promoter Variant of PIK3C3 Is Associated with Autoimmunity against Ro and Sm Epitopes in African-American Lupus Patients

The PIK3C3 locus was implicated in case-case genome-wide association study of systemic lupus erythematosus (SLE) which we had performed to detect genes associated with autoantibodies and serum interferon-alpha (IFN-α). Herein, we examine a PIK3C3 promoter variant (rs3813065/-442 C/T) in an independe...

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Hlavní autoři: Kariuki, Silvia N., Franek, Beverly S., Mikolaitis, Rachel A., Utset, Tammy O., Jolly, Meenakshi, Skol, Andrew D., Niewold, Timothy B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910508/
https://ncbi.nlm.nih.gov/pubmed/20671926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/826434
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