The Crohn's disease: associated ATG16L1 variant and Salmonella invasion

OBJECTIVE: A common genetic coding variant in the core autophagy gene ATG16L1 is associated with increased susceptibility to Crohn's disease (CD). The variant encodes an amino acid change in ATG16L1 such that the threonine at position 300 is substituted with an alanine (ATG16L1 T300A). How this...

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Main Authors: Messer, Jeannette S, Murphy, Stephen F, Logsdon, Mark F, Lodolce, James P, Grimm, Wesley A, Bartulis, Sarah J, Vogel, Tiphanie P, Burn, Melisa, Boone, David L
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2013
Assuntos:
Gastroenterology and Hepatology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686164/
https://ncbi.nlm.nih.gov/pubmed/23794574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2013-002790
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