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Transcription Factors and DNA Repair Enzymes Compete for Damaged Promoter Sites

Transcriptional regulation is a tightly regulated, vital process. The transcription factor cyclic AMP-response element-binding protein 1 (CREB1) controls ∼25% of the mammalian transcriptome by binding the CREB1 binding site consensus sequence (CRE) sequence (TGACGTCA). DNA lesions within CRE modulat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Moore, Stephen P. G., Kruchten, Joshua, Toomire, Kimberly J., Strauss, Phyllis R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786688/
https://ncbi.nlm.nih.gov/pubmed/26757817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.672733
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