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E2F1 Localizes to Sites of UV-induced DNA Damage to Enhance Nucleotide Excision Repair

The E2F1 transcription factor is a well known regulator of cell proliferation and apoptosis, but its role in the DNA damage response is less clear. Using a local UV irradiation technique and immunofluorescence staining, E2F1 is shown to accumulate at sites of DNA damage. Localization of E2F1 to UV-d...

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Detalhes bibliográficos
Main Authors: Guo, Ruifeng, Chen, Jie, Zhu, Feng, Biswas, Anup K., Berton, Thomas R., Mitchell, David L., Johnson, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885209/
https://ncbi.nlm.nih.gov/pubmed/20413589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.121939
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