Recruitment of the Nucleotide Excision Repair Endonuclease XPG to Sites of UV-Induced DNA Damage Depends on Functional TFIIH

The structure-specific endonuclease XPG is an indispensable core protein of the nucleotide excision repair (NER) machinery. XPG cleaves the DNA strand at the 3′ side of the DNA damage. XPG binding stabilizes the NER preincision complex and is essential for the 5′ incision by the ERCC1/XPF endonuclea...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Zotter, Angelika, Luijsterburg, Martijn S., Warmerdam, Daniël O., Ibrahim, Shehu, Nigg, Alex, van Cappellen, Wiggert A., Hoeijmakers, Jan H. J., van Driel, Roel, Vermeulen, Wim, Houtsmuller, Adriaan B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636808/
https://ncbi.nlm.nih.gov/pubmed/17000769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00695-06
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares