DNA damage stabilizes interaction of CSB with the transcription elongation machinery

The Cockayne syndrome B (CSB) protein is essential for transcription-coupled DNA repair (TCR), which is dependent on RNA polymerase II elongation. TCR is required to quickly remove the cytotoxic transcription-blocking DNA lesions. Functional GFP-tagged CSB, expressed at physiological levels, was hom...

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Detalhes bibliográficos
Main Authors: van den Boom, Vincent, Citterio, Elisabetta, Hoogstraten, Deborah, Zotter, Angelika, Egly, Jean-Marc, van Cappellen, Wiggert A., Hoeijmakers, Jan H.J., Houtsmuller, Adriaan B., Vermeulen, Wim
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172148/
https://ncbi.nlm.nih.gov/pubmed/15226310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200401056
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