Nuclear Dynamics of PCNA in DNA Replication and Repair

The DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) is central to both DNA replication and repair. The ring-shaped homotrimeric PCNA encircles and slides along double-stranded DNA, acting as a “sliding clamp” that localizes proteins to DNA. We determined the behavior of...

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Main Authors: Essers, Jeroen, Theil, Arjan F., Baldeyron, Céline, van Cappellen, Wiggert A., Houtsmuller, Adriaan B., Kanaar, Roland, Vermeulen, Wim
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Chromosome Structure and Dynamics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265825/
https://ncbi.nlm.nih.gov/pubmed/16227586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9350-9359.2005
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