DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A

Chromatin changes within the context of DNA repair remain largely obscure. Here we show that DNA damage induces monoubiquitylation of histone H2A in the vicinity of DNA lesions. Ultraviolet (UV)-induced monoubiquitylation of H2A is dependent on functional nucleotide excision repair and occurs after...

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Auteurs principaux: Bergink, Steven, Salomons, Florian A., Hoogstraten, Deborah, Groothuis, Tom A.M., de Waard, Harm, Wu, Junxin, Yuan, Li, Citterio, Elisabetta, Houtsmuller, Adriaan B., Neefjes, Jacques, Hoeijmakers, Jan H.J., Vermeulen, Wim, Dantuma, Nico P.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2006
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472908/
https://ncbi.nlm.nih.gov/pubmed/16702407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.373706
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