Recognition of DNA damage by XPC coincides with disruption of the XPC–RAD23 complex

The recognition of helix-distorting deoxyribonucleic acid (DNA) lesions by the global genome nucleotide excision repair subpathway is performed by the XPC–RAD23–CEN2 complex. Although it has been established that Rad23 homologs are essential to protect XPC from proteasomal degradation, it is unclear...

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Bibliografiske detaljer
Main Authors: Bergink, Steven, Toussaint, Wendy, Luijsterburg, Martijn S., Dinant, Christoffel, Alekseev, Sergey, Hoeijmakers, Jan H.J., Dantuma, Nico P., Houtsmuller, Adriaan B., Vermeulen, Wim
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2012
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308700/
https://ncbi.nlm.nih.gov/pubmed/22431748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107050
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