Recognition of DNA damage by XPC coincides with disruption of the XPC–RAD23 complex

The recognition of helix-distorting deoxyribonucleic acid (DNA) lesions by the global genome nucleotide excision repair subpathway is performed by the XPC–RAD23–CEN2 complex. Although it has been established that Rad23 homologs are essential to protect XPC from proteasomal degradation, it is unclear...

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Autors principals: Bergink, Steven, Toussaint, Wendy, Luijsterburg, Martijn S., Dinant, Christoffel, Alekseev, Sergey, Hoeijmakers, Jan H.J., Dantuma, Nico P., Houtsmuller, Adriaan B., Vermeulen, Wim
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2012
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308700/
https://ncbi.nlm.nih.gov/pubmed/22431748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107050
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