Definition of a Short Region of XPG Necessary for TFIIH Interaction and Stable Recruitment to Sites of UV Damage

XPG is the human endonuclease that cuts 3′ to DNA lesions during nucleotide excision repair. Missense mutations in XPG can lead to xeroderma pigmentosum (XP), whereas truncated or unstable XPG proteins cause Cockayne syndrome (CS), normally yielding life spans of <7 years. One XP-G individual who...

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Detalhes bibliográficos
Main Authors: Thorel, Fabrizio, Constantinou, Angelos, Dunand-Sauthier, Isabelle, Nouspikel, Thierry, Lalle, Philippe, Raams, Anja, Jaspers, Nicolaas G. J., Vermeulen, Wim, Shivji, Mahmud K. K., Wood, Richard D., Clarkson, Stuart G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC533987/
https://ncbi.nlm.nih.gov/pubmed/15572672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10670-10680.2004
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