Definition of a Short Region of XPG Necessary for TFIIH Interaction and Stable Recruitment to Sites of UV Damage

XPG is the human endonuclease that cuts 3′ to DNA lesions during nucleotide excision repair. Missense mutations in XPG can lead to xeroderma pigmentosum (XP), whereas truncated or unstable XPG proteins cause Cockayne syndrome (CS), normally yielding life spans of <7 years. One XP-G individual who...

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Bibliografiska uppgifter
Huvudupphovsmän: Thorel, Fabrizio, Constantinou, Angelos, Dunand-Sauthier, Isabelle, Nouspikel, Thierry, Lalle, Philippe, Raams, Anja, Jaspers, Nicolaas G. J., Vermeulen, Wim, Shivji, Mahmud K. K., Wood, Richard D., Clarkson, Stuart G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
DNA Dynamics and Chromosome Structure
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC533987/
https://ncbi.nlm.nih.gov/pubmed/15572672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10670-10680.2004
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