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Cellular Concentrations of DDB2 Regulate Dynamic Binding of DDB1 at UV-Induced DNA Damage

Nucleotide excision repair (NER) is the principal pathway for counteracting cytotoxic and mutagenic effects of UV irradiation. To provide insight into the in vivo regulation of the DNA damage recognition step of global genome NER (GG-NER), we constructed cell lines expressing fluorescently tagged da...

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Bibliographische Detailangaben
Hauptverfasser: Alekseev, Sergey, Luijsterburg, Martijn S., Pines, Alex, Geverts, Bart, Mari, Pierre-Olivier, Giglia-Mari, Giuseppina, Lans, Hannes, Houtsmuller, Adriaan B., Mullenders, Leon H. F., Hoeijmakers, Jan H. J., Vermeulen, Wim
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593426/
https://ncbi.nlm.nih.gov/pubmed/18936169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01108-08
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