PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1

The WD40-repeat protein DDB2 is essential for efficient recognition and subsequent removal of ultraviolet (UV)-induced DNA lesions by nucleotide excision repair (NER). However, how DDB2 promotes NER in chromatin is poorly understood. Here, we identify poly(ADP-ribose) polymerase 1 (PARP1) as a novel...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pines, Alex, Vrouwe, Mischa G., Marteijn, Jurgen A., Typas, Dimitris, Luijsterburg, Martijn S., Cansoy, Medine, Hensbergen, Paul, Deelder, André, de Groot, Anton, Matsumoto, Syota, Sugasawa, Kaoru, Thoma, Nicolas, Vermeulen, Wim, Vrieling, Harry, Mullenders, Leon
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471223/
https://ncbi.nlm.nih.gov/pubmed/23045548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112132
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados