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PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1
The WD40-repeat protein DDB2 is essential for efficient recognition and subsequent removal of ultraviolet (UV)-induced DNA lesions by nucleotide excision repair (NER). However, how DDB2 promotes NER in chromatin is poorly understood. Here, we identify poly(ADP-ribose) polymerase 1 (PARP1) as a novel...
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| Główni autorzy: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Rockefeller University Press
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471223/ https://ncbi.nlm.nih.gov/pubmed/23045548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112132 |
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