Comparative Analysis of Interaction of Human and Yeast DNA Damage Recognition Complexes with Damaged DNA in Nucleotide Excision Repair

The human XPC-RAD23B complex and its yeast ortholog, Rad4-Rad23, are the primary initiators of global genome nucleotide excision repair. The interaction of these proteins with damaged DNA was analyzed using model DNA duplexes containing a single fluorescein-substituted dUMP analog as a lesion. An el...

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Hauptverfasser: Krasikova, Yuliya S., Rechkunova, Nadejda I., Maltseva, Ekaterina A., Pestryakov, Pavel E., Petruseva, Irina O., Sugasawa, Kaoru, Chen, Xuejing, Min, Jung-Hyun, Lavrik, Olga I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
DNA and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624473/
https://ncbi.nlm.nih.gov/pubmed/23443653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.444026
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