DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression

Aging is a major risk factor for progression of liver diseases to hepatocellular carcinoma (HCC). Cellular senescence contributes to age-related tissue dysfunction, but the epigenetic basis underlying drug-induced senescence remains unclear.macroH2A1, a variant of histone H2A, is a marker of senesce...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: Borghesan, Michela, Fusilli, Caterina, Rappa, Francesca, Panebianco, Concetta, Rizzo, Giovanni, Oben, Jude A., Mazzoccoli, Gianluigi, Faulkes, Chris, Pata, Illar, Agodi, Antonella, Rezaee, Farhad, Minogue, Shane, Warren, Alessandra, Peterson, Abigail, Sedivy, John M., Douet, Julien, Buschbeck, Marcus, Cappello, Francesco, Mazza, Tommaso, Pazienza, Valerio, Vinciguerra, Manlio
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785885/
https://ncbi.nlm.nih.gov/pubmed/26772755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1336
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars